The Sales Lab

Gabriele Sales picture
I am a computational biologist interested in developing highly efficient methods for analysing large datasets generated by high‑throughput experimental techniques.
I take a multidisciplinary approach to the study of biological complexity, using techniques from computer science, statistics and systems biology.
My work focuses on the design of network-based methods for combining prior knowledge with new biomedical data, with the aim of creating predictive models and personalized treatments for diseases.

Gabriele Sales, PhD

Research Interests

Gabriele Sales designs algorithms and integration techniques for genomic data, high‑throughput sequencing and clinical studies.

Education

PhD, University of Turin

Selected Publications

  • Ilenia Urso, Alberto Biscontin, Davide Corso, Cristiano Bertolucci, Chiara Romualdi, Cristiano De Pittà, Bettina Meyer, Gabriele Sales. A thorough annotation of the krill transcriptome offers new insights for the study of physiological processes. Scientific Reports 12, 11415 (2022). [PubMed], [PDF]
  • Paolo Martini, Gabriele Sales, Linda Diamante, Valentina Perrera, Chiara Colantuono, Sara Riccardo, Davide Cacchiarelli, Chiara Romualdi, Graziano Martello. BrewerIX enables allelic expression analysis of imprinted and X-linked genes from bulk and single-cell transcriptomes. Communications Biology 5, 146 (2022). [Pubmed], [PDF]
  • Andrew J Modzelewski, Wanqing Shao, Jingqi Chen, Angus Lee, Xin Qi, Mackenzie Noon, Kristy Tjokro, Gabriele Sales, Anne Biton, Aparna Anand, Terence P Speed , Zhenyu Xuan, Ting Wang, Davide Risso, Lin He. A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. Cell S0092-8674(21)01104-1 (2021). [Pubmed], [PDF]
  • Gabriele Sales, Enrica Calura, Chiara Romualdi. metaGraphite - a new layer of pathway annotation to get metabolite networks. Bioinformatics 35, 1258–1260 (2019). [Pubmed], [PDF]
  • Jong Wook Kim, Olga B Botvinnik, Omar Abudayyeh, Chet Birger, Joseph Rosenbluh, Yashaswi Shrestha, Mohamed E Abazeed, Peter S Hammerman, Daniel DiCara, David J Konieczkowski, Cory M Johannessen, Arthur Liberzon, Amir Reza Alizad-Rahvar, Gabriela Alexe, Andrew Aguirre, Mahmoud Ghandi, Heidi Greulich, Francisca Vazquez, Barbara A Weir, Eliezer M Van Allen, Aviad Tsherniak, Diane D Shao, Travis I Zack, Michael Noble, Gad Getz, Rameen Beroukhim, Levi A Garraway, Masoud Ardakani, Chiara Romualdi, Gabriele Sales, David A Barbie, Jesse S Boehm, William C Hahn, Jill P Mesirov, Pablo Tamayo. Characterizing genomic alterations in cancer by complementary functional associations. Nature Biotechnology 34, 539–546 (2016). [Pubmed], [PDF]
  • Gabriele Sales, Enrica Calura, Paolo Martini, Chiara Romualdi. Graphite Web: Web tool for gene set analysis exploiting pathway topology. Nucleic Acids Research, 41 (W1): W89-W97 (2013). [Pubmed], [PDF]
  • Gabriele Sales, Enrica Calura, Duccio Cavalieri, Chiara Romualdi. graphite - a Bioconductor package to convert pathway topology to gene network. BMC Bioinformatics, 13:20 (2012). [Pubmed], [PDF]